MAIL Notification Object fails with SMTP error

Document ID : KB000117706
Last Modified Date : 23/10/2018
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Issue:
Error Description: 

Mail object is getting failed with the error "SMTP Client cannot connect to the SMTP Server x.x.x.x, error code ''10013 , error description: 'access right problem' ".
 
Environment:
Any OS
Cause:
Investigation:

- Disabled Anitvirus 
- Windows Firewall is off 
- Tested send_mail() function inside Process tab script and this was successful. 
- Ran a Powershell script on the Automation Engine machine to send email and this was successful. 
Resolution:
Unistalling McAfee Virus Scan Console completely (not just disabling it) resolved this issue.