Is there any cases in the past that a problem occurred to Site Minder after applying following patches of Microsoft?
KB4457144 (Monthly Rollup)
KB4457918 (Security and Quality Rollup updates for .NET Framework 3.5.1, 4.5.2, 4.6, 4.6.1, 4.6.2, 4.7, 4.7.1, and 4.7.2 for Windows 7 SP1 and Windows Server 2008 R2 SP1)
KB4343205 (Cumulative security update for Internet Explorer)
KB890830 (Windows Malicious Removal Tool)
CA SiteMinder R12.52 SP1
OS : WindowsServer2008 R2
Regarding the above mentioned patches of Microsoft, past cases like having problems with SiteMinder after applying the patches was not found. (As of 2018 SEP)