In 12.1 the SOLVESSI running with UNIX=YES does all the Unix commands. Many USS NETSTAT and other calls are made, depending on how the product is used. Attempting to change the home directory may effect stack monitoring of IP, TCP and UDP. It may also cause other unexpected results that we cannot foresee.
We recommend stopping both the SOLVESSI and the Netmaster region prior to changing the OMVS home directory.